|
|
L-isoleucine + H2O + O2 <=> 3-methyl-2-oxopentanoate + NH3 + H2O2
|
1.4.3.2
L-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS259006
SABIO-RK:
2170
|
|
|
|
3-methyl-2-oxopentanoate + NADPH <=> 2-hydroxy-3-methylpentanoate + NADP+
|
1.1.1.169
2-dehydropantoate 2-reductase
|
–
|
|
|
BRENDA:
BS371870
SABIO-RK:
6885
|
|
|
|
D-Leu + H2O + O2 <=> 3-methyl-2-oxopentanoate + NH3 + H2O2
|
1.4.3.3
D-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS372934
|
|
|
|
D-isoleucine + H2O + O2 <=> 3-methyl-2-oxopentanoate + NH3 + H2O2
|
1.4.3.3
D-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS259047
|
|
|
|
3-methyl-2-oxopentanoate + CoA + oxidized_ferredoxin <=> 2-methylbutanoyl-CoA + CO2 + reduced_ferredoxin
|
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
|
–
|
B
|
|
BRENDA:
BS359414
|
|
|
|
L-alpha-hydroxy-beta-methylvalerate + O2 <=> 3-methyl-2-oxopentanoate + H2O2
|
1.1.3.2
L-lactate oxidase
|
–
|
|
|
BRENDA:
BS443672
|
|
|
|
D-isoleucine + H2O + O2 <=> 3-methyl-2-oxopentanoate + H2O2
|
1.4.3.19
glycine oxidase
|
–
|
|
|
BRENDA:
BS372924
|
|
|
|
L-alpha-hydroxy-beta-methylvalerate + 2,6-dichlorophenolindophenol <=> 3-methyl-2-oxopentanoate + reduced_2,6-dichlorophenolindophenol
|
1.1.3.15
(S)-2-hydroxy-acid oxidase
|
–
|
|
|
BRENDA:
BS257456
|
|
|
|
L-isoleucine + 3-Indole-2-oxopropanoate <=> 3-methyl-2-oxopentanoate + L-tryptophan
|
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
|
|
|
BRENDA:
BS437637
|
|
|
|
L-isoleucine + H2O + 2 cytochrome_b <=> 3-methyl-2-oxopentanoate + NH3 + 2 reduced_cytochrome_b
|
1.4.99.B3
|
–
|
|
|
BRENDA:
BS439669
|
|
|
|
L-leucine + 3-methyl-2-oxopentanoate <=> 4-methyl-2-oxopentanoate + L-isoleucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356501
|
|
|
|
L-isoleucine + 3-methyl-2-oxopentanoate <=> 4-methyl-2-oxopentanoate + L-isoleucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356531
|
|
|
|
3-methyl-2-oxopentanoate + reduced_methyl_viologen <=> 2-hydroxy-3-methylpentanoate + methyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
|
BRENDA:
BS371398
|
|
|
|
L-kynurenine + 3-methyl-2-oxopentanoate <=> Kynurenic_acid + L-isoleucine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353518
|
|
|
|
L-allo-isoleucine + 2-oxoglutarate <=> 3-methyl-2-oxopentanoate + L-glutamate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356541
|
|
|
|
DL-Ile + 2-oxoglutarate <=> 3-methyl-2-oxopentanoate + L-glutamate
|
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
|
–
–
|
|
|
BRENDA:
BS356540
|
|
|
|
3-methyl-2-oxopentanoate + NADH <=> 2-hydroxy-3-methylpentanoate + NAD+
|
1.1.1.27
L-lactate dehydrogenase
1.1.1.345
D-2-hydroxyacid dehydrogenase (NAD+)
|
–
–
|
|
|
BRENDA:
BS187995
|
|
|
|
L-allo-isoleucine + H2O + NAD+ <=> 3-methyl-2-oxopentanoate + NADH + NH3
|
1.4.1.20
phenylalanine dehydrogenase
|
–
|
|
|
BRENDA:
BS232350
|
|
|
|
L-leucine + H2O + NAD+ <=> 3-methyl-2-oxopentanoate + NH3 + NADH
|
1.4.1.20
phenylalanine dehydrogenase
|
–
|
|
|
BRENDA:
BS232340
|
|
|
|
D-isoleucine + H2O + methylene_blue <=> 3-methyl-2-oxopentanoate + NH3 + reduced_methylene_blue
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS260548
|
|
|
|
3-methyl-2-oxopentanoate + reduced_benzyl_viologen <=> 2-hydroxy-3-methylpentanoate + Oxidized_benzyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
|
BRENDA:
BS371397
|
|
|
|
L-allo-isoleucine + 4-methyl-2-oxopentanoate <=> 3-methyl-2-oxopentanoate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356545
|
|
|
|
3-methyl-2-oxopentanoate + NADPH + NH3 <=> L-isoleucine + NADP+ + H2O
|
1.4.1.2
glutamate dehydrogenase
|
–
|
|
|
BRENDA:
BS387198
|
|
|
|
3-methyl-2-oxopentanoate + NH3 + NADPH + H+ <=> D-isoleucine + H2O + NADP+
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS425133
|
|
|
|
L-allo-isoleucine + 2-oxoisovalerate <=> 3-methyl-2-oxopentanoate + L-valine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356543
|
|
|
|
L-isoleucine + 4-methylsulfanyl-2-oxobutanoate <=> 3-methyl-2-oxopentanoate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.57
aromatic-amino-acid transaminase
|
–
–
|
|
|
BRENDA:
BS353576
|
|
|
|
L-isoleucine + 2-oxobutyrate <=> 3-methyl-2-oxopentanoate + 2-aminobutanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356524
|
|
|
|
L-allo-isoleucine + 2-oxobutyrate <=> 3-methyl-2-oxopentanoate + 2-aminobutanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356542
|
|
|
|
L-allo-isoleucine + 2-oxooctanoate <=> 3-methyl-2-oxopentanoate + 2-aminooctanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356539
|
|
|
|
3-methyl-2-oxopentanoate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
|
BRENDA:
BS231866
|
|
|
|
L-allo-isoleucine + 2-Oxohexanoate <=> 3-methyl-2-oxopentanoate + 2-aminohexanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356544
|
|
|
|
L-isoleucine + 3-methylthio-2-oxobutanoate <=> 3-methyl-2-oxopentanoate + 2-amino-3-methylthiobutanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356525
|
|
|
|
2R,3S-2,3-dihydroxy-3-methylpentanoate <=> 3-methyl-2-oxopentanoate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
|
|
BRENDA:
BS453487
|
|
|
|
3-methyl-2-oxopentanoate <=> Isovaleraldehyde + CO2
|
4.1.1.72
branched-chain-2-oxoacid decarboxylase
|
–
|
|
|
BRENDA:
BS427984
|
|
|
|
2,3-dihydroxy-3-methylpentanoate <=> 3-methyl-2-oxopentanoate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
B
|
|
BRENDA:
BS18755
|
|
|
|
oxaloaspartate + L-isoleucine <=> L-aspartate + 3-methyl-2-oxopentanoate
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS437785
|
|
|
|
2-oxoglutarate + L-isoleucine <=> L-aspartate + 3-methyl-2-oxopentanoate
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS437789
|
|
|
|
L-isoleucine + oxaloacetate <=> 3-methyl-2-oxopentanoate + L-aspartate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356523
|
|
|
|
L-isoleucine + glyoxylate <=> 3-methyl-2-oxopentanoate + glycine
|
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS354037
|
|
|
|
3-methyl-2-oxopentanoate + glyoxylate <=> L-isoleucine + glycine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS436790
|
|
|
|
L-glutamine + 3-methyl-2-oxopentanoate <=> 2-Oxoglutaramate + L-isoleucine
|
2.6.1.64
glutamine---phenylpyruvate transaminase
|
–
|
|
|
BRENDA:
BS356776
|
|
|
|
pyruvate + L-isoleucine <=> L-alanine + 3-methyl-2-oxopentanoate
|
2.6.1.12
alanine---oxo-acid transaminase
2.6.1.51
serine---pyruvate transaminase
|
–
–
|
|
|
BRENDA:
BS353457
|
|
|
|
phenylpyruvate + DL-Ile <=> L-phenylalanine + 3-methyl-2-oxopentanoate
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
|
–
|
|
|
BRENDA:
BS356436
|
|
|
|
L-isoleucine + phenylpyruvate <=> L-phenylalanine + 3-methyl-2-oxopentanoate
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
|
–
|
|
|
BRENDA:
BS452222
|
|
|
|
D-isoleucine + O2 + H2O <=> H2O2 + 3-methyl-2-oxopentanoate + NH3
|
1.4.3.3
D-amino-acid oxidase
|
–
|
|
|
SABIO-RK:
8112
|
|
|
|
NAD+ + 3-methyl-2-oxopentanoate + CoA <=> CO2 + H+ + NADH + 2-methylbutanoyl-CoA
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
|
SABIO-RK:
3001
|
|
|
|
H+ + NADPH + 3-methyl-2-oxopentanoate <=> 2-hydroxyisocaproate + NADP+
|
1.1.1.272
D-2-hydroxyacid dehydrogenase (NADP+)
|
–
|
|
|
SABIO-RK:
14682
|
|
|
|
H+ + 3-methyl-2-oxopentanoate + NADH <=> 2-hydroxyisocaproate + NAD+
|
1.1.1.345
D-2-hydroxyacid dehydrogenase (NAD+)
|
–
|
|
|
SABIO-RK:
14683
|
|
|
|
3-methyl-2-oxopentanoate + H2O + 5,10-methylenetetrahydrofolate <=> 3-(Hydroxymethyl)-3-methyl-2-oxopentanoic_acid + tetrahydrofolate
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
|
SABIO-RK:
14655
|
|